South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America


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7-Day Mexican Riviera
Los Angeles, California | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles, California
20 Feb 2027
7 Nights
Discovery Princess
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Interest free Monthly Payments from JUST £17pp
Cruise Only From
Was £459pp
Now: £436 pp
REF: PRINCESSX709
Antarctic Encounter
Buenos Aires | Buenos Aires | Buenos Aires | Port Stanley | Port Stanley | Port Stanley | Port Stanley | Port Stanley | Ushuaia | Punta Arenas | Punta Arenas | Punta Arenas | Puerto Montt | Puerto Montt | More...
20 Feb 2027
18 Nights
Seven Seas Mariner
South America
Fly Cruise From
Was £12569pp
Now: £11940 pp
REF: REGENTMAR270220
6-Day Mexican Riviera
Long Beach, California | Cabo San Lucas | Cabo San Lucas | Ensenada | Long Beach, California
21 Feb 2027
6 Nights
Carnival Panorama
West Coast US
Seas & Sights Sale! Call for a Cruise118.com Package price and receive up to £150 OFF per stateroom - for a limited time only
Cruise Only From
Was £419pp
Now: £402 pp
REF: CARNIVALPO210220276
Exotic Coasts & Casco Viejo
Miami, Florida | Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Roatán Island | Georgetown, Grand Cayman | Ocho Rios | Ocho Rios | Puerto Limón | Puerto Limón | Cartagena | Colón | Panama City | More...
23 Feb 2027
14 Nights
Seven Seas Grandeur
South America
Fly Cruise From
Was £8564pp
Now: £8135 pp
REF: REGENTGRA270223
Antarctica in Depth
Buenos Aires | Buenos Aires | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia
25 Feb 2027
12 Nights
Scenic Eclipse II
Antarctica
Fly Cruise From

Now: £14919 pp
REF: SCENIC101S250227-1
8-Day Mexican Riviera
Long Beach, California | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach, California
27 Feb 2027
8 Nights
Carnival Panorama
West Coast US
Seas & Sights Sale! Call for a Cruise118.com Package price and receive up to £150 OFF per stateroom - for a limited time only
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Cruise Only From
Was £628pp
Now: £603 pp
REF: CARNIVALPO270220278
7-Day Mexican Riviera
Los Angeles, California | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles, California
27 Feb 2027
7 Nights
Discovery Princess
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Interest free Monthly Payments from JUST £17pp
Cruise Only From
Was £459pp
Now: £436 pp
REF: PRINCESSX710
14 Night Patagonia & Argentina Cruise
Buenos Aires | Montevideo | Port Stanley | Port Stanley | Ushuaia | Ushuaia | Punta Arenas | Puerto Madryn | Punta del Este | Buenos Aires
27 Feb 2027
14 Nights
Celebrity Equinox
South America
Book online for EXTRA savings, best prices and live availability
NEW! Up to 75% OFF 2nd Guest PLUS save up to £500 per stateroom
Interest free Monthly Payments from JUST £54pp
Cruise Only From
Was £1556pp
Now: £1431 pp
REF: CELEBEQ14F118-270227
Fjords & Glaciers of Southern Chile & Patagonia
Buenos Aires | Ushuaia | Cape Horn | Chilean Fjords | Chilean Fjords | Aguila Glacier | Tuckers Islets | Magdalena Island | Admiralty Bay, Bequia | Admiralty Bay, Bequia | Punta Arenas | Punta Arenas | Isla Pinguino | Puerto Deseado | More...
28 Feb 2027
17 Nights
Scenic Eclipse
South America
Fly Cruise From

Now: £9754 pp
REF: SCENIC701L280227-2
19 nights - San Antonio to Fort Lauderdale - February 2027
San Antonio | San Antonio | Coquimbo | Arica | Callao | Callao | Manta | Fuerte Amador | Fuerte Amador | Aruba | Fort Lauderdale, Florida
28 Feb 2027
19 Nights
Queen Anne
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Cunard NEW season NOW on sale + 10% Early booking savings - October 2026 - April 2027
Reduced Saver Fares! HUGE savings when you book your cruise with Cruise118.com
Interest free Monthly Payments from JUST £139pp
Fly Cruise From
Was £3874pp
Now: £3758 pp
REF: CUNARDH706
33 nights - San Antonio to Southampton - February 2027
San Antonio | San Antonio | Coquimbo | Arica | Callao | Callao | Manta | Fuerte Amador | Fuerte Amador | Aruba | Fort Lauderdale, Florida | Port Canaveral, Florida | Ponta Delgada, Azores | Southampton More...
28 Feb 2027
33 Nights
Queen Anne
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Cunard NEW season NOW on sale + 10% Early booking savings - October 2026 - April 2027
Reduced Saver Fares! HUGE savings when you book your cruise with Cruise118.com
Interest free Monthly Payments from JUST £159pp
Fly Cruise From
Was £4409pp
Now: £4277 pp
REF: CUNARDH706A
36 nights - San Antonio to Hamburg - February 2027
San Antonio | San Antonio | Coquimbo | Arica | Callao | Callao | Manta | Fuerte Amador | Fuerte Amador | Aruba | Fort Lauderdale, Florida | Port Canaveral, Florida | Ponta Delgada, Azores | Southampton | More...
28 Feb 2027
36 Nights
Queen Anne
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Cunard NEW season NOW on sale + 10% Early booking savings - October 2026 - April 2027
Reduced Saver Fares! HUGE savings when you book your cruise with Cruise118.com
Fly Cruise From
Was £15599pp
Now: £15131 pp
REF: CUNARDH706B
Panama Canal: Bahamas & Costa Rica
Miami, Florida | Great Stirrup Cay | Cabo Rojo | Oranjestad | Willemstad | Cartagena | Colón | Gatun Lake | Puerto Limón | Miami, Florida
01 Mar 2027
12 Nights
Norwegian Sun
Panama Canal
CRUISE118.COM EXCLUSIVE! Upgrade to half price More at Sea from £125pp
Up to 50% OFF all cruises! Up to £250 airfare credit, plus 3rd & 4th guest pay taxes only!
Interest free Monthly Payments from JUST £66pp
Cruise Only From

Now: £1673 pp
REF: NCLSUN-20270301-12-MIA-MIA
7-Day Mexican Riviera
Los Angeles, California | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles, California
06 Mar 2027
7 Nights
Discovery Princess
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Interest free Monthly Payments from JUST £19pp
Cruise Only From
Was £537pp
Now: £510 pp
REF: PRINCESSX711
6-Day Mexican Riviera
Long Beach, California | Cabo San Lucas | Cabo San Lucas | Ensenada | Long Beach, California
07 Mar 2027
6 Nights
Carnival Panorama
West Coast US
Seas & Sights Sale! Call for a Cruise118.com Package price and receive up to £150 OFF per stateroom - for a limited time only
Cruise Only From
Was £497pp
Now: £477 pp
REF: CARNIVALPO070320276
Journey To The Amazon
Panama City | Panama City | Panama City | Oranjestad | Oranjestad | Port-of-Spain | Port-of-Spain | Port-of-Spain | Macapa | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | More...
09 Mar 2027
22 Nights
Seven Seas Grandeur
South America
Fly Cruise From
Was £10444pp
Now: £9921 pp
REF: REGENTGRA270309
Machu Picchu & Mayan Ruins
Callao | Callao | Salaverry | Salaverry | Guayaquil | Manta | Manta | Golfito | Panama City | Panama City | Puerto Limón | Puerto Limón | Roatán Island | Harvest Caye | More...
10 Mar 2027
16 Nights
Seven Seas Mariner
South America
Fly Cruise From
Was £10399pp
Now: £9879 pp
REF: REGENTMAR270310
8-Day Mexican Riviera
Long Beach, California | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach, California
13 Mar 2027
8 Nights
Carnival Panorama
West Coast US
Seas & Sights Sale! Call for a Cruise118.com Package price and receive up to £150 OFF per stateroom - for a limited time only
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Cruise Only From
Was £666pp
Now: £639 pp
REF: CARNIVALPO130320278
7-Day Mexican Riviera
Los Angeles, California | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles, California
13 Mar 2027
7 Nights
Discovery Princess
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Interest free Monthly Payments from JUST £19pp
Cruise Only From
Was £537pp
Now: £510 pp
REF: PRINCESSX712
11-day Cruise on Norwegian Sun
Miami, Florida | Falmouth | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami, Florida
13 Mar 2027
11 Nights
Norwegian Sun
Panama Canal
CRUISE118.COM EXCLUSIVE! Upgrade to half price More at Sea from £125pp
Up to 50% OFF all cruises! Up to £250 airfare credit, plus 3rd & 4th guest pay taxes only!
Interest free Monthly Payments from JUST £61pp
Cruise Only From

Now: £1560 pp
REF: NCLSUN-20270313-11-MIA-MIA
7-Day Mexican Riviera
Los Angeles, California | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles, California
20 Mar 2027
7 Nights
Discovery Princess
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Interest free Monthly Payments from JUST £19pp
Cruise Only From
Was £537pp
Now: £510 pp
REF: PRINCESSX713
6-Day Mexican Riviera
Long Beach, California | Cabo San Lucas | Cabo San Lucas | Ensenada | Long Beach, California
21 Mar 2027
6 Nights
Carnival Panorama
West Coast US
Seas & Sights Sale! Call for a Cruise118.com Package price and receive up to £150 OFF per stateroom - for a limited time only
Cruise Only From
Was £512pp
Now: £492 pp
REF: CARNIVALPO210320276
Panama Canal: Mexico, Jamaica & Costa Rica
Miami, Florida | Georgetown, Grand Cayman | Falmouth | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami, Florida
24 Mar 2027
12 Nights
Norwegian Sun
Panama Canal
CRUISE118.COM EXCLUSIVE! Upgrade to half price More at Sea from £125pp
Up to 50% OFF all cruises! Up to £250 airfare credit, plus 3rd & 4th guest pay taxes only!
Interest free Monthly Payments from JUST £63pp
Cruise Only From

Now: £1675 pp
REF: NCLSUN-20270324-12-MIA-MIA
8-Day Mexican Riviera
Long Beach, California | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach, California
27 Mar 2027
8 Nights
Carnival Panorama
West Coast US
Seas & Sights Sale! Call for a Cruise118.com Package price and receive up to £150 OFF per stateroom - for a limited time only
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Cruise Only From
Was £705pp
Now: £677 pp
REF: CARNIVALPO270320278
7-Day Mexican Riviera
Los Angeles, California | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles, California
27 Mar 2027
7 Nights
Discovery Princess
South America
BLACK NOVEMBER ONLINE DEAL! Save up to an extra £50 per stateroom
Interest free Monthly Payments from JUST £19pp
Cruise Only From
Was £537pp
Now: £510 pp
REF: PRINCESSX714

Prices are subject to change and availability. Prices may vary depending on airport selected. Promotions are only applicable to select cabins grades, please call for details

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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